83-5980-46　PCLO (ACZ, PCH3, Piccolo, Aczonin) (PE) 100ug　051987-PE

特徴

• PCLO (piccolo, also known as aczonin) is a large (more than 400kD) multidomain protein of the presynaptic cytomatrix in neurons, that is present in all vertebrate synapses, but is absent from invertebrates.
• It contains zinc finger and coiled-coil sequences, as well as N-terminal glutamine-rich sequence, and C-terminal PDZ domain followed by two C2 domains (C2A and C2B).
• In vitro binding and transfection experiments suggested that PCLO binds to multiple proteins including profilin and L-type calcium channels.
• It is involved in neurotransmitter release and insulin secretion.
• Applications:Suitable for use in Flow Cytometry.
• Other applications not tested.
• Recommended Dilutions:Flow Cytometry: 1-5ug/ml, intracellular staining
• Optimal dilutions to be determined by the researcher.
• Storage and Stability:Store product at 4℃ in the dark.
• DO NOT FREEZE! Stable at 4℃ for 12 months after receipt as an undiluted liquid.
• Dilute required amount only prior to immediate use.
• Further dilutions can be made in assay buffer.
• Caution: PE conjugates are sensitive to light.
• For maximum recovery of product, centrifuge the original vial prior to removing the cap.