CD218a, an ~62kD type I transmembrane glycoprotein, is the alpha subunit of IL-18 receptor heterodimer.
It is expressed in various immune cells, including lymphocytes, NK cells, and myeloid cells, as well as in heart, lung, liver, gut and another tissues.
IL-18 is a proinflammatory cytokine, that promotes both Th1 and Th2 immune responses, induces IFN-gamma production and activates NK cells.
Applications:Suitable for use in Western Blot, Immunohistochemistry, Flow Cytometry and Immunoprecipitation.
Other applications not tested.
Recommended Dilutions:Flow Cytometry: 1-4ug/mlImmunohistochemistry: frozen and paraffin sectionsOptimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4℃ for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20℃.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:100ug
抗体種類:Mab
宿主:mouse
Source Antibody:human
Grade:Affinity Purified
Purity:Purified by Protein A affinity chromatography.
Form:Supplied as a liquid in PBS, pH 7.4, 0.09% sodium azide
Specificity:Recognizes an extracellular epitope of human CD218a
Clone # USB:H44
Isotype:IgG1,k
Calc Applications Abbrev:FC IHC IP WB
Calc Crossreactivity:Hu
Immunogen:Human CD218a expressed on a transfected NK0 cell line