83-5979-51　CD111 100ug　048929

特徴

• CD111, also known as nectin-1, is a calcium-independent cell-cell adhesion transmembrane glycoprotein involved in organization of adherens junctions and tight junctions in epithelial and endothelial cells.
• It also serves as a target molecule for entry of herpes simplex virus (HSV-1, HSV-2) and pseudorabies virus (PRV) into epithelial and neuronal cells.
• CD111 is connected with actin cytoskeleton through afadin.
• Mutations in the gene for CD111 cause cleft lip and palate/ectodermal dysplasia 1 syndrome (CLPED1) as well as non-syndromic cleft lip with or without cleft palate (CL/P).
• Alternative splicing results in multiple transcript variants encoding proteins with distinct C-termini.
• Applications:Suitable for use in Immunoprecipitation, Immunohistochemistry, Western Blot, Flow Cytometry and Immunocytochemistry.
• Other applications have not been tested.
• Recommended Dilutions:Flow Cytometry: 1-4ug/mlOptimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4℃ for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20℃.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.