83-5979-13　Fatty Acid Binding Protein 7 (FABP7) 100ul　048716

特徴

• FABP7 is a member of the large family of hydrophobic ligand-binding proteins.
• FABP proteins are involved in lipid metabolism, including uptake and intracellular trafficking of fatty acids and retinoids.
• In addition, they play a role in gene regulation, cell signaling, cell growth and differentiation.
• Several reports have suggested a possible role for the different FABP proteins in cancer biology, linking their levels with either increasing or decreasing the degree of malignancy.
• Nine FABPs (FABP1-FABP9) have been identified.
• FABP7 is a brain-specific protein that is required for the establishment of the radial glial fiber system in the developing brain, a system that is necessary for the migration of immature neurons to establish cortical layers.
• It is expressed at high levels in the developing central nervous system.
• FABP7 has also been found in melanocytic lesions and has shown to regulate proliferation and invasion in melanoma cells in vitro, suggesting that it may play a role in cell proliferation and invasion.
• Applications:Suitable for use in Immunofluorescence, Immunocytochemistry and Western Blot.
• Not recommended for use in Immunohistochemistry.
• Other applications not tested.
• Recommended Dilutions:Western Blot: 1:1000-1:2000Immunofluorescence (IC): 1:1000Optimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4℃ for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20℃.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.