83-5978-79　Galectin-9 (HUAT, LGalS9A, LEG9) 100ug　048689

特徴

• Galectin-9 is a glycan-binding protein, which is expressed in three main isoforms of 49 aa, 27 aa, and 15 aa.
• It can be detected on the cell surface, as well as intracellularly, or in a secreted form.
• On the cell surface, galectin-9 plays roles in contacts with other cells and with extracellular matrix.
• It is expressed on multiple cell types, but mainly on Treg cells, activated Th cells and some cancers.
• Its secreted form acts like a cytokine with immunomodulatory and immunosuppresive functions.
• Massive and inadequate production of galectin-9, associated with some viral infections or cancers, can counteract immune reactions to these illnesses.
• High levels of galectin-9 expression lead to poor prognosis of cancer patients.
• Applications:Suitable for use in Flow Cytometry and Immunohistochemistry.
• Other applications not tested.
• Recommended Dilution:Flow Cytometry: 1-4ug/ml using intracellular staining
• Optimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4℃ for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20℃.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.