CD61, known as integrin b3 or glycoprotein IIIa (gpIIIa), is a 90 kD type I integral transmembrane glycoprotein.
It is a member of integrin family that associates with platelet gpIIb (CD41) forming CD41/CD61 complex and associates with integrin aV (CD51) forming aV/b3 (CD51/CD61) integrin.
CD41/CD61 is expressed on platelets and megakaryocytes, and plays a role in platelet activation and aggregation through interaction with fibrinogen, fibronectin, vWF and other RGD-containing adhesion molecules.
CD51/CD61 is expressed on platelets, osteoclasts, fibroblast, macrophages and some tumor cells, involved in tumor metastasis and in adenovirus infection through binding to RGD motif ECM proteins.
Applications:Suitable for use in Flow Cytometry.
Other applications not tested.
Recommended Dilution:Flow Cytometry: 5ul/10e6 cells in 100ulOptimal dilutions to be determined by the researcher.
Storage and Stability:Store product at 4℃ in the dark.
DO NOT FREEZE! Stable at 4℃ for 12 months after receipt as an undiluted liquid.
Dilute required amount only prior to immediate use.
Further dilutions can be made in assay buffer.
Caution: APC conjugates are sensitive to light.
For maximum recovery of product, centrifuge the original vial prior to removing the cap.
仕様
Size：100Tests
抗体種類：Mab
宿主：mouse
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by affinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.2, BSA, 0.09% sodium azide. Labeled with Allophycocyanin (APC).
Specificity：Recognizes human CD61. Species Crossreactivity: cynomolgus and rhesus monkey
