Cadherin-13, also known as H-Cadherin and T-Cadherin, is a GPI-linked calcium dependent adhesion molecule that is predominantily expressed in heart and brain.
Cadherin-13 negatively influences cell growth and is down regulated in some cancers.
A 116 residue N-terminal propeptide is proteolytically removed to generate mature Cadherin-13.
Human and mouse proCadherin-13 share 95% amino acid identity.
Applications:Suitable for use in Flow Cytometry.
Other applications not tested.
Recommended Dilutions:Flow Cytometry: 10ul labels 10e6 cells using NCI-H460 human large cell lung carcinoma cell line
Optimal dilutions to be determined by the researcher.
Excitation:488nm
Emission:565-605nm
Storage and Stability:Store product at 4℃ in the dark.
DO NOT FREEZE! Stable at 4℃ for 12 months after receipt as an undiluted liquid.
Dilute required amount only prior to immediate use.
Further dilutions can be made in assay buffer.
Caution: PE conjugates are sensitive to light.
For maximum recovery of product, centrifuge the original vial prior to removing the cap.
仕様
Size：100Tests
抗体種類：Mab
宿主：rat
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by Protein G affinity chromatography from hybridoma culture supernatent
Form：Supplied as a liquid in saline, 0.5% BSA, 0.09% sodium azide. Labeled with R-Phycoerythrin (PE).
Specificity：Recognizes human Cadherin-13. Does not cross-react with recombinant human ECAD, NCAD, PCAD, VECAD, hCAD-8, CAD-11, CAD-12 or CAD-17.
Clone # USB：7H192
Isotype：IgG2a
Calc Applications Abbrev：FC
Calc Crossreactivity：Hu
Immunogen：Recombinant protein corresponding to Glu23-Ala692 of human Cadherin-13 expressed in NS0 cells
