CD39, also known as ectonucleoside triphosphate diphosphohydrolase 1 (ENTPD1), is a cell surface enzyme (with intracellular N- and C-terminus) which hydrolyzes extracellular ATP and ADP to AMP.
Inhibition of its enzymatic activity may confer anticancer benefits.
The formation of oligomers in the plasma membrane is essential for enzyme activity.
It is expressed on Treg cells, and in other cell types, such as mantle zone B cells, activated T cells, NK cells, macrophages, dendritic cells, neurons, endothelial cells and platelets.
Hydrolysis of ATP and ADP inhibits inflammatory and thrombotic responses.
In the nervous system, it regulates purinergic neurotransmission.
Applications:Suitable for use in Flow Cytometry.
Other applications not tested.
Recommended Dilutions:Flow Cytometry: 4ul labels 10e6 cells in 100ulOptimal dilutions to be determined by the researcher.
Storage and Stability:Store product at 4℃ if to be used immediately within two weeks.
For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20℃.
Aliquots are stable at -20℃ for 12 months after receipt.
Dilute required amount only prior to immediate use.
Further dilutions can be made in assay buffer.
Caution: FITC conjugates are sensitive to light.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100Tests
抗体種類：Mab
宿主：mouse
Source Antibody：human
Grade：Purified
Purity：Purified
Form：Supplied as a liquid in PBS, pH 7.4, 15mM sodium azide. Labeled with Fluorescein isothiocyanate (FITC).
