CD31 is a 130-140kD glycoprotein, also known as platelet endothelial cell adhesion molecule (PECAM-1), EndoCAM, and gpIIa.
It is a member of the Ig superfamily, expressed on endothelial cells, platelets, granulocytes, monocytes/macrophages, dendritic cells, and T and B cell subsets, and is critical for cell-to-cell interactions.
The primary ligands for CD31 have been reported to be CD38 and the vitronectin receptor (av b3 integrin, CD51/CD61).
Other reported functions of CD31 are neutrophil emigration to sites of inflammation, and angiogenesis.
This antibody has been shown to inhibit in vitro and in vivo functions of CD31.
Applications:Suitable for use in Flow Cytometry.
Other applications not tested.
Recommended Dilution:Flow Cytometry: ≤0.25ug/10e6 cells in 100ulOptimal dilutions to be determined by the researcher.
Storage and Stability:Store product at 4℃ in the dark.
DO NOT FREEZE! Stable at 4℃ for 12 months after receipt as an undiluted liquid.
Dilute required amount only prior to immediate use.
Further dilutions can be made in assay buffer.
Caution: APC conjugates are sensitive to light.
For maximum recovery of product, centrifuge the original vial prior to removing the cap.
仕様
Size:100ug
抗体種類:Mab
宿主:rat
Source Antibody:mouse
Grade:Affinity Purified
Purity:Purified by affinity chromatography.
Form:Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide. Labeled with Allophycocyanin (APC).
Specificity:Recognizes mouse CD31.
Clone # USB:MEC13.3
Isotype:IgG2a,k
Calc Applications Abbrev:FC
Calc Crossreactivity:Mo
Immunogen:Polyoma middle T transformed EC line tEnd.1