Rhodopsin is a multi-pass, G-protein-coupled membrane receptor protein belonging to the G-protein coupled receptor 1 family.
Found within rod photoreceptor cells, rhodopsin is activated by light photons in order for the visual transduction cascade to initialize.
Rhodopsin is necessary to the forming of images in low light and for the viability of photoreceptor cells after birth.
Mutations in rhodopsin expression are the most widely known cause of the human disease retinitis pigmentosa (RP) resulting in gradual loss of vision.
At present, there are over 100 known rhodopsin mutations.
Applications:Suitable for use in ELISA, Immunocytochemistry, Western Blot and Immunohistochemistry.
Other applications not tested.
Recommended Dilutions:Immunohistochemistry (paraffin): 1:500 detected Rhodopsin in rat eye tissue using heat-induced epitope retrieval in citrate buffer, pH 6.0
Optimal dilutions to be determined by the researcher.
Positive Control:Rat eye tissue
Storage and Stability:May be stored at 4℃ for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20℃.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ug
抗体種類：Mab
宿主：mouse
Source Antibody：rat
Grade：Affinity Purified
Purity：Purified by Protein G affinity chromatography.
Form：Supplied as a liquid in 0.1M Tris-glycine, pH 7.4, 0.15M sodium chloride, 0.05% sodium azide.
Specificity：Recognizes rat rhodopsin. Species Crossreactivity: human
Clone # USB：4D2
Isotype：IgG2b,k
Calc Applications Abbrev：E IC IHC WB
Calc Crossreactivity：Hu Rt
Immunogen：Rat rod outer segments corresponding to rat Rhodopsin at the N-terminus. Species Sequence Homology: mouse (100%)
