83-5976-80　CD279 (PD-1, Programmed Cell Death 1) (PE) 100Tests　046241-PE

特徴

• CD279 / PD-1 (programmed cell death 1), a transmembrane protein of CD28/CTLA-4 family.
• It is expressed inducibly mainly on activated T, B, and myeloid cells and plays a role in maintaining peripheral self-tolerance.
• Binding to its ligands CD273 and CD274 is associated with inhibition of T cell proliferation and induction of their anergy.
• It is also expressed during thymic development.
• Some variants of CD279 are associated with susceptibility to systemic lupus erythematosus, type 1 diabetes, and rheumatoid arthritis.
• Applications:Suitable for use in Flow Cytometry.
• Other applications not tested.
• Recommended Dilution:Flow Cytometry: 10ul labels 10e6 cells in 100ulOptimal dilutions to be determined by the researcher.
• Storage and Stability:Store product at 4℃ in the dark.
• DO NOT FREEZE! Stable at 4℃ for 12 months after receipt as an undiluted liquid.
• Dilute required amount only prior to immediate use.
• Further dilutions can be made in assay buffer.
• Caution: PE conjugates are sensitive to light.
• For maximum recovery of product, centrifuge the original vial prior to removing the cap.