83-5976-74　CD273 (Butyrophilin, B7-DC, Programmed Cell Death 1 Ligand 2, PD-1 Ligand 2, PDCD1 Ligand 2, PDCD1L2, PDCD1LG2, Programmed Death Ligand 2, PDL2, PD-L2) (APC) 100Tests　046239-APC

特徴

• CD273 / PD-L2 (programmed death ligand-1), also known as B7-DC, is a member of the B7 family of regulatory proteins.
• It costimulates the proliferation of T cells, and mediates IFN gamma production.
• Ligation of CD273 on dendritic cells enhances dendritic cell activation and T cell responses.
• When interacting with CD279, it can act as a coinhibitor of the T cell function.
• CD273 expression is a useful marker to distinguish primary mediastinal B cell lymphoma from other diffuse large B cell lymphomas.
• Applications:Suitable for use in Flow Cytometry.
• Other applications not tested.
• Recommended Dilutions:Flow Cytometry: 10ul labels 10e6 cells in 100ulOptimal dilutions to be determined by the researcher.
• Storage and Stability:Store product at 4℃ in the dark.
• DO NOT FREEZE! Stable at 4℃ for 12 months after receipt as an undiluted liquid.
• Dilute required amount only prior to immediate use.
• Further dilutions can be made in assay buffer.
• Caution: APC conjugates are sensitive to light.
• For maximum recovery of product, centrifuge the original vial prior to removing the cap.