83-5976-72 CD273 (Butyrophilin, B7-DC, Programmed Cell Death 1 Ligand 2, PD-1 Ligand 2, PDCD1 Ligand 2, PDCD1L2, PDCD1LG2, Programmed Death Ligand 2, PDL2, PD-L2) 100ug 046239
特徴
- CD273 / PD-L2 (programmed death ligand-1), also known as B7-DC, is a member of the B7 family of regulatory proteins.
- It costimulates the proliferation of T cells, and mediates IFN gamma production.
- Ligation of CD273 on dendritic cells enhances dendritic cell activation and T cell responses.
- When interacting with CD279, it can act as a coinhibitor of the T cell function.
- CD273 expression is a useful marker to distinguish primary mediastinal B cell lymphoma from other diffuse large B cell lymphomas.
- Applications:Suitable for use in Flow Cytometry and Immunohistochemistry.
- Other applications not tested.
- Recommended Dilutions:Flow Cytometry: 1-4ug/mlOptimal dilutions to be determined by the researcher.
- Storage and Stability:May be stored at 4℃ for short-term only.
- Aliquot to avoid repeated freezing and thawing.
- Store at -20℃.
- Aliquots are stable for 12 months after receipt.
- For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
- Size:100ug
- 抗体種類:Mab
- 宿主:mouse
- Source Antibody:human
- Grade:Affinity Purified
- Purity:Purified by Protein A affinity chromatography
- Form:Supplied as a liquid in PBS, pH 7.4, 15mM sodium azide
- Specificity:Recognizes human CD273.
- Clone # USB:24F.10C12
- Isotype:IgG2a,k
- Calc Applications Abbrev:FC IHC
- Calc Crossreactivity:Hu
- Immunogen:Human CD273 cDNA
- Swiss Prot Number:Q9BQ51
- EU Commodity Code:30021010
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