CD138 (syndecan 1) is a transmembrane proteoglycan that can bind a variety of cytokines and modulate their activity, as well as the activity of extracellular matrix components and influence many developmental processes.
CD138 is expressed mainly in differentiating keratinocytes and is transiently upregulated in all layers of the epidermis upon tissue injury.
It is also highly expressed on plasma cells and can be detected even on fibroblasts, vascular smooth muscle cells and endothelial cells.
Up-regulation and down-regulation of CD138 on the cell surface often correlates with the gain of cancerous characteristics.
Serum levels of the shedded soluble sCD138 are used as a prognostic factor of cancerogenesis.
Applications:Suitable for use in Flow Cytometry.
Other applications have not been tested.
Recommended Dilutions:Flow Cytometry: 10ul labels 10e6 cells of 100ul whole blood or 1x10e6 cells in suspensionOptimal dilutions to be determined by the researcher.
Storage and Stability:Store product at 4℃ in the dark.
DO NOT FREEZE! Stable at 4℃ for 12 months after receipt as an undiluted liquid.
Dilute required amount only prior to immediate use.
Further dilutions can be made in assay buffer.
Caution: PE conjugates are sensitive to light.
For maximum recovery of product, centrifuge the original vial prior to removing the cap.
仕様
Size：100Tests
抗体種類：Mab
宿主：mouse
Source Antibody：human
Grade：Purified
Purity：Purified
Form：Supplied as a liquid in PBS, pH 7.4, 15mM sodium azide. Labeled with R-Phycoerythrin (PE).
Specificity：Recognizes human CD138. Species Crossreactivity: non-human primates
Clone # USB：MI15
Isotype：IgG1,k
Calc Applications Abbrev：FC
Calc Crossreactivity：Hu Mk
Immunogen：A mixture of U266 and XG-1 human myeloma cell lines
