Integrin alpha 4 / beta 7 (CD49d / Ly69) , also known as LPAM-1 (Llmphocyte Peyer´s patch adhesion molecule 1), is a heterodimeric (150 kDa / 130 kDa) integrin complex which mediates lymphocyte homing to Peyer´s patch high endothelial venules and to the intestinal lamina propria.
It is expressed primarily on mucosal lymphocytes, but is also present on NK cells and eosinophils.
Ligands of LPAM-1 are MAdCAM-1, VCAM-1, and fibronectin, but the alpha 4 subunit (CD49d) can mediate also homotypic adhesion.
Applications:Suitable for use in Flow Cytometry, Immunoprecipitation and Immunohistochemistry.
Other applications not tested.
Recommended Dilution:Flow Cytometry: 1-4ug/mlImmunohistochemistry: frozenOptimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4℃ for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20℃.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:100ug
抗体種類:Mab
宿主:rat
Source Antibody:mouse
Grade:Affinity Purified
Purity:Purified by Protein G affinity chromatography.
Form:Supplied as a liquid in PBS, pH 7.4, 15mM sodium azide.