83-5975-23　Galectin-3 (Gal-3, 35kD Lectin, Carbohydrate-binding Protein 35, CBP 35, Galactose-specific Lectin 3, Galactoside-binding Protein, GALBP, IgE-binding Protein, L-31, Laminin-binding Protein, Lectin L-29, Mac-2 Antigen, LGALS3, MAC2) (PE) 200ug　046103

特徴

• Galectin-3 (galactose-specific lectin 3) is a 30-32kD glycoprotein, also known as Mac-2, Gal-3, RL-29, galactose-specific lectin 3, CBP-35, L-34, and eBP.
• It is a member of the animal B-galactoside-binding lectin family that is expressed in the cell nucleus, cytoplasm, plasma membrane, or extracellular matrix by variety of tumor cells, monocytes/macrophages, epithelial cells, Kupffer cells, and dendritic cells.
• Galectin-3 contains carbohydrate recognition domains and binds to B-galactoside residues bearing glycoproteins, such as as IgE, IgA, galactose, casein kinase I, laminin, mucin, LAMPs, and CD66.
• Galectin-3 is an adhesion molecule and plays an important role in regulation of cell proliferation, differentiation and tumor cell metastasis.
• Structurally, Galectin-3 possesses NWGR motif that is conserved in the BH-1 domain of the BCL-2 family and functions as an apoptotic molecule.
• Applications:Suitable for use in Flow Cytometry Other applications not tested.
• Recommended Dilutions:Flow Cytometry: ≤0.25ug/ml/10e6 cells in 100ulOptimal dilutions to be determined by the researcher.
• Storage and Stability:Store product at 4℃ in the dark.
• DO NOT FREEZE! Stable at 4℃ for 12 months after receipt as an undiluted liquid.
• Dilute required amount only prior to immediate use.
• Further dilutions can be made in assay buffer.
• Caution: PE conjugates are sensitive to light.
• For maximum recovery of product, centrifuge the original vial prior to removing the cap.