HLA-C, a member of MHC class I glycoproteins, is one of polymorphysm typing targets, which are important for transplantation.
The HLA system plays an important role in the occurrence and outcome of infectious diseases.
The structural spike and the nucleocapsid proteins of the novel coronavirus SARS-CoV-2, which causes coronavirus disease 2019 (COVID-19), are reported to contain multiple Class I epitopes with predicted HLA restrictions.
Individual HLA genetic variation may help explain different immune responses to a virus across a population.
It has been described that HLA-C interacts with human herpesvirus 8 MIR1 protein.
Applications: Suitable for use in Flow Cytometry.
Other applications not tested.
Recommended Dilution:Flow Cytometry: 10ul labels 100ul of whole blood or 10e6 cells in a suspension
Optimal dilutions to be determined by the researcher.
Storage and Stability:Store product at 4℃ in the dark.
DO NOT FREEZE! Stable at 4℃ for 12 months after receipt as an undiluted liquid.
Dilute required amount only prior to immediate use.
Further dilutions can be made in assay buffer.
Caution: PE conjugates are sensitive to light.
For maximum recovery of product, centrifuge the original vial prior to removing the cap.
仕様
Size：100Tests
抗体種類：Mab
宿主：mouse
Grade：Purified
Purity：Purified
Form：Supplied as a liquid in PBS, pH 7.4, 15mM sodium azide. Labeled with R-Phycoerythrin (PE).
Specificity：Recognizes an extracellular epitope on HLA-C member of MHC class I molecules. Species Crossreactivity: human and primate. Does not crossreact with HLA-A or HLA-B allotypes.
Clone # USB：DT-9
Isotype：IgG2b
Calc Applications Abbrev：FC
Calc Crossreactivity：Hu Mk
Immunogen：Purified MHC class I molecules of tamarin origin
