83-5973-77　Glial Fibrillary Acidic Protein (GFAP) 50ul　045845

特徴

• Glial Fibrillary Acidic Protein (GFAP) is strongly and specifically expressed in astrocytes, Bergmann glia and certain other glia in the central nervous system, in satellite cells in peripheral ganglia, and in non-myelinating Schwann cells in peripheral nerves (1-3).
• GFAP expression is also seen in developing neural stem cells and GFAP levels may greatly increase in regions of CNS injury or disease (4), and point mutations in the GFAP gene are causative of Alexander’s disease (5).
• Antibodies to GFAP such as 045845 are useful for visualizing glia and monitoring developmental, disease and damage related CNS alterations.
• This antibody has been shown to work well on western blots, IF, ICC and IHC of human.
• pig and cow samples.
• Some interest has recently been focused on GFAP as a protein released into blood and CSF following traumatic brain injury, stroke and other CNS compromises (6).
• Measurement of the levels of blood or CSF GFAP may give information about patient presention, progress, response to therapy or outcome.
• Applications:Suitable for use in Immunofluorescence, Immunocytochemistry, Immunohistochemistry and Western Blot.
• Other applications not tested.
• Recommended Dilution:Immunofluorescence (IC): 1:500Western Blot: 1:2000Immunohistochemistry (paraffin): 1:2000Optimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4℃ for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20℃.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.