83-5973-20 C5aR2 (G-Protein Coupled Receptor 77, GPCR77, GPR77, C5L2, C5a Anaphylatoxin Chemotactic Receptor) (APC) 100Tests G8600-81E-APC
特徴
- C5aR2, also known as C5L2, is one of two receptors for C5a (anaphylatoxin).
- It is coexpressed with C5aR1 (CD88) in neutrophils, as well as e.g.
- in mast cells, astrocytes, or macrophages, and seems to have both pro-inflammatory and anti-inflammatory roles, depending on circumstances.
- Unlike CD88, C5aR2 is not coupled to G-protein, thus the modulatory role is more likely.
- Applications:Suitable for use in Flow Cytometry.
- Other applications not tested.
- Recommended Dilution:Flow Cytometry: 10ul labels 10e6 cells in 100ulOptimal dilutions to be determined by the researcher.
- Storage and Stability:Store product at 4℃ in the dark.
- DO NOT FREEZE! Stable at 4℃ for 12 months after receipt as an undiluted liquid.
- Dilute required amount only prior to immediate use.
- Further dilutions can be made in assay buffer.
- Caution: APC conjugates are sensitive to light.
- For maximum recovery of product, centrifuge the original vial prior to removing the cap.
仕様
- Size:100Tests
- 抗体種類:Mab
- 宿主:mouse
- Source Antibody:human
- Grade:Purified
- Purity:Purified
- Form:Supplied as a liquid in PBS, pH 7.4, 15mM sodium azide. Labeled with Allophycocyanin (APC).
- Specificity:Recognizes human C5L2. Species Crossreactivity: primate
- Clone # USB:1D9-M12
- Isotype:IgG2a,k
- Calc Applications Abbrev:FC
- Calc Crossreactivity:Hu
- Immunogen:L1.2 cells transfected with human C5aR2
- Swiss Prot Number:Q9P296
- EU Commodity Code:30021010
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