83-5973-01　CD49b (Integrin a2) 100ul　045719

特徴

• CD49b is a 170 kD transmembrane protein, also known as α2 integrin, VLA-2 α chain, Integrin α2 and GPIa.
• It associates with CD29 (β1 integrin) to form VLA-2, a collagen and laminin receptor on many cell types including monocytes, platelets, activated T cells, megakaryocytes, neuronal cells, epithelial cells, and osteoclasts.
• CD49b has been reported to interact with F-actin and matrix metalloproteinase 1.
• CD49b is a platelet alloantigen and has been associated with neonatal alloimmune thrombocytopenia.
• Deficiencies in this protein have been associated with hemorrhagic disorders.
• Applications:Suitable for use in Immunohistochemistry.
• Other applications not tested.
• Recommended Dilutions:Immunohistochemistry (frozen sections): 1:1000.
• Pretreatment: NoneIncubation: 60 minutes at room temperatureOptimal dilutions to be determined by the researcher.
• Immunohistochemistry Positive Control:Normal Human Kidney
• Storage and Stability:May be stored at 4℃ for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20℃.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.