83-5972-74　Influenza (Influenza H5, Influenza NP-A, Influenza A virus Hemagglutinin Glycoprotein, Influenza A virus HA, HA, Hemagglutinin) 200ug　045691

特徴

• Hemagglutinin is an antigenic glycoprotein which allows viral attachment and entry into the cell.
• Sixteen subtypes of Hemagglutinin (H1-H16) have been described, of which H1, H2 and H3 infect humans.
• H5 and H7 normally result in avian disease, with some highly pathogenic H5N1 strains causing 100% mortality in poultry.
• H5N1 has in some cases mutated to infect humans, with 60% mortality.
• Hemagglutinin H5 is from the Influenza A virus H5N1.
• Influenza A belongs to the Orthomyxoviridae family, and is a negative sense single-stranded RNA virus which results in respiratory disease.
• Hemagglutinin is one of the most medically relevant antigens on influenza as it is a target for antiviral drugs and antibodies.
• Applications:Suitable for use in ELISA, Indirect Immunofluorescent, Virus Titration, Hemagglutination Inhibition and Microneutralization.
• Other applications not tested.
• Recommended Dilution:Optimal dilutions to be determined by the researcher.
• Application Notes:In the original study, this antibody was used in conjunction with other mAbs (e.g.
• N2B10 mAb specific for the head of seasonal H3 HA; T2-9A mAb specific for the head of H1N1pdm09) for enzyme-linked immunosorbent, indirect immunofluorescent, virus titration, hemagglutination inhibition (HAI), and microneutralization (MN) assays to show that assessing antigenic relatedness of evolving influenza viruses with panels of defined, renewable, and human monoclonal antibodies could be a very useful an adjunct to ferret antisera in detection of antigenic drift and in the selection of viruses for inclusion in influenza vaccines (Huang et al., 2015).
• Storage and Stability:May be stored at 4℃ for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20℃.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.