Clostridium difficile is a gram positive motile bacterium which is the leading cause of diarrhea in developed countries.
The incidence of disease in humans varies greatly with age, spore density and the administration of antibiotics.
Toxin B (TcdB) is a large exotoxin.
Its role in disease is less well understood than that of toxin A, though it seems clear that TcdB contributes to disease.
Both toxins modifies the Ras superfamily of small GTPases via glycosylation, inactivating them and leading to the disruption of vital signaling pathways in the cell.
Applications:Suitable for use in ELISA.
Other applications not tested.
Recommended Dilutions:ELISA: 1:20-1:200Optimal dilutions to be determined by the researcher.
Matched Pair:Capure: 592435Detection: 592436
Storage and Stability:May be stored at 4℃ for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20℃.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：1mg
抗体種類：Mab
宿主：mouse
Grade：Affinity Purified
Purity：Purified by Protein A affinity chromatography from ascites.
Form：Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Specificity：Recognizes glutamate dehydrogenase of Clostridium difficile. Does not react with with mammalian cells.
