83-5965-56 TRAIL, Drozitumab Biosimilar 100ug 591802
特徴
- Drozitumab Biosimilar uses the same protein sequences as the therapeutic antibody drozitumab.
- Drozitumab is a human monoclonal antibody in development for the treatment of cancers.
- It targets Tumor Necrosis Factor Related Apoptosis-inducing Ligand (TRAIL), whose receptors are found on the surface of many types of malignant cells.
- Although drozitumab was studied in phase II trials for treating chondrosarcoma, colorectal cancer, non-Hodgkin lymphoma, and non-small cell lung cancer, development has been halted due to lack of clinical response.
- Applications:Suitable for use in ELISA, Neutralization, Functional Assays such as bioanalytical PK and ADA assays, and those assays for studying biological pathways affected by Drozitumab.
- Other applications not tested.
- Recommended Dilution:Optimal dilutions to be determined by the researcher.
- Storage and Stability:May be stored at 4℃ for short-term only.
- Aliquot to avoid repeated freezing and thawing.
- Store at -20℃.
- Aliquots are stable for 12 months after receipt.
- For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
- Size:100ug
- 抗体種類:Mab
- 宿主:human
- Source Antibody:human
- Grade:Highly Purified
- Purity:≥95% (reducing SDS-PAGE, HPLC). Endotoxin: ≤1EU/mg (LAL)
- Form:Supplied as a 0.2uM filtered solution, pH 6.0. No stabilizers or preservatives added.
- Specificity:Recognizes the in vivo grade TRAIL biosimilar which specifically binds to death receptor DR5 and induces apoptosis.
- Isotype:IgG1,k
- Calc Applications Abbrev:E N
- Calc Crossreactivity:Hu
- Immunogen:Recombinant protein corresponding to humam TRAIL, Drozitumab biosimilar, produced in mammalian cells.
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商品のバリエーション (サイズ違い・スペック違い・オプション品など)
| 商品イメージ | アズワン品番 商品名 |
|---|---|
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83-5965-56
TRAIL, Drozitumab Biosimilar 100ug
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83-5965-57
TRAIL, Drozitumab Biosimilar 1mg
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