Tumor necrosis factor alpha (TNFalpha) is a cytokine produced primarily by monocytes and macrophages.
It is found in synovial cells and macrophages in the tissues.The primary role of TNFalpha is in the regulation of immune cells.
TNFalpha is able to induce apoptotic cell death, to induce inflammation, and to inhibit tumorigenesis and viral replication.
Dysregulation of TNFalpha production has been implicated in a variety of human diseases, including major depression, Alzheimer's disease and cancer.
Recombinant TNFalpha is used as an immunostimulant under the INN tasonermin.
TNFalpha can be produced ectopically in the setting of malignancy and parallels parathyroid hormone both in causing secondary hypercalcemia and in the cancers with which excessive production is associated.
Applications:Suitable for use in ELISA and SDS-PAGE.
Other applications not tested.
Recommended Dilution:Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4℃ for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20℃.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ug
抗体種類：Mab
宿主：chimeric
Grade：Highly Purified
Purity：≥95%
Form：Supplied as a liquid in PBS, pH 7.5.
Specificity：Recognizes Certolizumab.
Isotype：Fab-IgG1
Calc Applications Abbrev：E
Immunogen：Recombinant protein corresponding to Certolizumab, expressed in CHO cells.
