83-5964-50　CD30, Brentuximab Biosimilar (TNFRSF8) 5mg　591723

特徴

• Human CD30 is also known as TNFRSF8, is a cell membrane protein of the tumor necrosis factor receptor family and tumor marker.
• TNFRSF-8 is expressed by activated, but not by resting, T and B cells.
• Also, CD30 is expressed on classical Hodgkin Lymphoma cells together with CD15.
• CD30 is the receptor for TNFSF8/CD30L.
• CD30 can interact with TRAF2 and TRAF5, and mediate the signal transduction that leads to the activation of NF-kappa-B.
• TNFRSF8 may play a role in the regulation of cellular growth and transformation of activated lymphoblasts.
• TNFRSF8 is a positive regulator of apoptosis, and also has been shown to limit the proliferative potential of autoreactive CD8 effector T cells and protect the body against autoimmunity.
• Applications:Suitable for use in Functional Assays.
• Other applications not tested.
• Recommended Dilution:Optimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4℃ for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20℃.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.