DR5 is a 55kD member 10B of the TNF receptor superfamily (TNFRSF10B), also known as TRAIL-R2, TRICK2, KILLER, and CD262.
It binds the cytotoxic ligand TRAIL and induces apoptosis.
The DR5 receptor is broadly expressed on a variety of normal tissues and many tumors.
DR5 expression has been reported to be upregulated in human cells by interferon-alpha, 2-methoxyestradiol, and paclitaxel, and downregulated by adenoviral E3 proteins.
Applications:Suitable for use in Flow Cytometry.
Other applications have not been tested.
Recommended Dilutions:Flow Cytometry: ≤1ug/10e6 cells in 100ulOptimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4℃ for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20℃.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ug
抗体種類：Mab
宿主：mouse
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by affinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Specificity：Recognizes human TRAIL-R2.
Clone # USB：DJR2-4 (7-8)
Isotype：IgG1,k
Calc Applications Abbrev：FC
Calc Crossreactivity：Hu
Immunogen：Extracellular domain of DR5-human IgG1 Fc fusion protein
