This antibody is useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin's lymphomas.
The most common feature of these malignancies is the restricted expression of a single heavy chain class.
Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is clonal and therefore malignant.
Applications:Suitable for use in Immunohistochemistry.
Other applications not tested.
Recommended Dilution:Immunohistochemistry (formalin-fixed paraffin sections): 1-2ug/ml for 30 min at RT.
Requires HIER: boil tissue sections in 10mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 min
Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4℃ for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20℃.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:100ug
抗体種類:Mab
宿主:rabbit
Source Antibody:human
Grade:Affinity Purified
Purity:Purified by Protein A affinity chromatography.
Form:Supplied as a liquid in PBS, 0.1mg/mL BSA, 0.05% sodium azide.
Specificity:Recognizes a protein of 75kD, identified as gamma heavy chain of human immunoglobulins. Reacts with all sub-classes of gamma chain of human immunoglobulins. Does not cross-react with alpha (IgA), mu (IgM), epsilon (IgE), or delta (IgD), heavy chains, T-cells, monocytes, granulocytes, or erythrocytes.