The cytoskeleton-linking membrane protein of 62kD (CLIMP-63) is a marker for the reticular subdomain of the rough endoplasmatic reticulum (ER) and is excluded from the outer nuclear membrane.
Concentration of CLIMP-63 into patches may enhance microtubule binding on the cytosolic side and contribute to ER morphology by the formation of a protein scaffold in the lumen of the ER, linking the rough ER to microtubules.
Applications:Suitable for use in ELISA, Western Blot, Immunoprecipitation, Immunohistochemistry, Immunocytochemistry and Flow Cytometry.
Other applications not tested.
Recommended Dilution:Immunohistochemistry: frozen sectionsOptimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4℃ for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20℃.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:100ug
抗体種類:Mab
宿主:mouse
Grade:Affinity Purified
Purity:Purified by Protein G affinity chromatography from hybridoma tissue culture supernatant.
Form:Supplied as a liquid in PBS, 0.09% sodium azide
Specificity:Recognizes human CLIMP-63. Species Crossreactivity: monkey
Clone # USB:G1/296
Isotype:IgG2a,k
Calc Applications Abbrev:E FC IC IHC IP WB
Calc Crossreactivity:Hu Mk
Immunogen:Human CLIMP-63 (cytoskeleton-linking membrane protein of 63kD) from Caco-2 cells golgi membrane fraction.