HLA-C, a member of MHC class I glycoproteins, is one of polymorphysm typing targets, which are important for transplantation.
The HLA system plays an important role in the occurrence and outcome of infectious diseases.
The structural spike and the nucleocapsid proteins of the novel coronavirus SARS-CoV-2, which causes coronavirus disease 2019 (COVID-19), are reported to contain multiple Class I epitopes with predicted HLA restrictions.
Individual HLA genetic variation may help explain different immune responses to a virus across a population.
It has been described that HLA-C interacts with human herpesvirus 8 MIR1 protein.
Applications: Suitable for use in Flow Cytometry and Immunoprecipitation.
Other applications not tested.
Recommended Dilution:Flow Cytometry: 1-4ug/mlOptimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4℃ for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20℃.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ug
抗体種類：Mab
宿主：mouse
Grade：Affinity Purified
Purity：Purified by Protein A affinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.4, 15mM sodium azide
Specificity：Recognizes an extracellular epitope on HLA-C member of MHC class I molecules. Species Crossreactivity: human and primate. Does not crossreact with HLA-A or HLA-B allotypes.
Clone # USB：DT-9
Isotype：IgG2b
Calc Applications Abbrev：FC IP
Calc Crossreactivity：Hu Mk
Immunogen：Purified MHC class I molecules of tamarin origin
