83-5959-39　Lysosome Associated Membrane Protein 2 (LAMP 2, CD107b, Igp2, Igp110) (HRP) 100ul　L9190-15D-HRP

特徴

• Lysosomes are membrane-bound organelles found within the cytoplasm of most cells, which contain hydrolytic enzymes and act as the major compartment for heterophagic and autophagic digestion.
• Members of the lysosomal-associated membrane protein family (LAMPS) are believed to play an important role in protecting the lysosomal membrane from protease degradation and are involved in lectin-mediated cell adhesion.
• Evidence shows that CD107b is involved in the lysosomal uptake of cytosolic proteins and the endocytic pathway and human studies have revealed a correlation between the level of surface expression of CD107b on tumor cells and their metastatic potential.
• Applications:Suitable for use in Western Blot, Electron Microscopy, Immunoprecipitation and Immunofluorescence.
• Other applications not tested.
• Recommended Dilutions:Optimal dilutions to be determined by the researcher.
• Hybridoma:Spleen cells from immunized BALB/c mice were fused with cells of the NS1 myeloma cell line.
• Storage and Stability:Store product at 4℃ if to be used immediately within two weeks.
• For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20℃.
• Aliquots are stable at -20℃ for 12 months after receipt.
• Dilute required amount only prior to immediate use.
• Further dilutions can be made in assay buffer.
• Note: Sodium azide is a potent inhibitor of peroxidase and should not be added to HRP conjugates.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
• Note: Applications are based on unconjugated antibody.