83-5958-19　Carcinoembryonic Antigen (CEA, Carcinoembryonic Antigen-related Cell Adhesion Molecule 5, CEACAM5, CD66e, CD66e Antigen) 100ug　135943

特徴

• The CD66e (CEA; 180-200kD) is a member of carcinoembryonic antigens, immunoglobulin supergene family and consists of a single N domain (structural homology to the immunoglobulin variable) and six immunoglobulin constant-like A (A1, A2, A3) and B domains (B1, B2, B3).
• Human CD66e is heavily glycosylated GPI anchored protein capable of both homophilic and heterophilic adhesion.
• Disease relevance: The CD66e may play a role in the process of metastasis of cancer cells.
• CD66e is found in serum and it is clinically used as a tumor marker for early detection of disease due to its expression in adenocarcinomas - potential target of tumor imaging and drug targeting.
• Applications:Suitable for use in Flow Cytometry, Immunoprecipitation, Immunohistochemistry.
• Other applications not tested.
• Recommended Dilution:Immunohistochemistry (Paraffin): 10ug/ml Requires pepsin digestion
• Immunohistochemistry: FrozenOptimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4℃ for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20℃.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.