Tartrate-resistant acid phosphatase type 5 (TRAcP), also referred to as Acp5, is secreted by osteoclasts during bone resorption.
Release of TRAcP was stimulated by resorbogenic cytokines and repressed by calcitonin (a resorption inhibitor).
TRAcP is also known to be expressed in high quantities in active macrophages and dendritic cells and play an essential part in presenting antigens to T cells.
Inactive TRAcP released from adipose tissue macrophages has been shown to bring on hyperplastic obesity, keeping lipid metabolism and insulin sensitivity normal.
Applications:Suitable for use in Western Blot, Dot Blot, ELISA, Immunoprecipitation, Immunocytochemistry and Immunohistochemistry.
Other applications not tested.
Recommended Dilutions:Western Blot: 1:500 detected TRAcP in large malignant B-cells in hairy cell leukemia tissue
Optimal dilutions to be determined by the researcher.
Positive Control:Large malignant B-cells in hairy cell leukemia tissue
Storage and Stability:May be stored at 4℃ for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20℃.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ug
抗体種類：Mab
宿主：mouse
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by Protein G affinity chromatography.
Form：Supplied as a liquid in 0.1M Tris-Glycine, pH 7.4, 150mM sodium chloride, 0.05% sodium azide.
Specificity：Recognizes human TRAcP.
Clone # USB：9C5
Isotype：IgG2b,k
Calc Applications Abbrev：DB E IC IHC IP WB
Calc Crossreactivity：Hu
Immunogen：Full length purified protein corresponding to human TRAcP.
