ADAM22 is a member of the ADAM (a disintegrin and metalloprotease domain) family, implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis.
Unlike other members of the ADAM protein family, the protein encoded by this gene lacks metalloprotease activity since it has no zinc-binding motif.
The protein is highly expressed in the brain and may function as an integrin ligand in the brain.
In mice, it has been shown to be essential for correct myelination in the peripheral nervous system.
Applications:Suitable for use in Western Blot Other applications have not been tested.
Recommended Dilutions:Western Blot: 1-10ug/mlOptimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4℃ for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20℃.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:100ul
抗体種類:Mab
宿主:mouse
Source Antibody:mouse
Grade:Affinity Purified
Purity:Purified by affinity chromatography.
Form:Supplied as a liquid in PBS.
Specificity:Recognizes mouse ADAM22. Species Crossreactivity: rat
Clone # USB:N46/30
Isotype:IgG2b,k
Calc Applications Abbrev:WB
Calc Crossreactivity:Mo Rt
Immunogen:Fusion protein corresponding to amino acids 757-857 (cytoplasmic region) of mouse ADAM22 protein.