Blood group related antigens represent a group of carbohydrate determinants carried on both glycolipids and glycoproteins.
They are usually mucin-type, and are detected on erythrocytes, certain epithelial cells, and in secretions of certain individuals.
Sixteen genetically and biosynthetically distinct but inter-related specificities belong to this group of antigens, including A, B, H, Lewis A, Lewis B, Lewis X, Lewis Y, and precursor type 1 chain antigens.
Increased expression of Lewis B has been reported in gastric and pancreatic tumors, as well as in colorectal cancer.
Applications:Suitable for use in ELISA, Western Blot and Immunohistochemistry.
Storage and Stability:May be stored at 4℃ for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20℃.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ug
抗体種類：Mab
宿主：mouse
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by Protein A affinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.4, 0.09% sodium azide.
Specificity：Recognizes human Lewis B, a carbohydrate determinant carried on both glycolipids and glycoproteins, detected on erythrocytes, certain epithelial cells and in secretions of certain individuals.
Clone # USB：2-25LE
Isotype：IgG1
Calc Applications Abbrev：E IHC WB
Calc Crossreactivity：Hu
Immunogen：Lewis B isolated by size exclusion chromatography from an ovarian cyst fluid (pure endocervical type according to the Fenoglio´s classification).
