Immunoglobulin E (IgE) is a 180kD soluble protein serving as an antigen-specific unit of mast cell effector mechanisms.
IgE has the lowest serum concentration of all immunoglobulins (~0.5mg/l) in healthy individuals, but upon allergen challenge its concentration in blood increases dramatically.
Although biological survival of free IgE is very short (T1/2 = 2 days), it is stabilized after binding to its high affinity receptor.
Unlike IgM- IgG- and IgA-committed B cells, IgE-switched B cells do not undergo clonal expansion.
Applications:Suitable for use in Flow Cytometry and ELISA.
Other applications not tested.
Recommended Dilutions:Flow Cytometry: 5ug/mlOptimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4℃ for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20℃.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:100ug
抗体種類:Mab
宿主:mouse
Source Antibody:human
Grade:Affinity Purified
Purity:Purified by Protein A affinity chromatography.
Form:Supplied as a liquid in PBS, pH 7.4, 15mM sodium azide