The adenomatous polyposis coli tumor suppressor gene is mutated (often deletion of the C-terminal portion of APC) in the inherited disease, familial adenomatous polyposis (FAP), and over 80% of colorectal cancers.
C-APC 28.8 can be used for APC expression and detection of APC mutations.
Applications:Suitable for use in Immunofluorescence, Western Blot, Immunoprecipitation and Immunohistochemistry.
Other applications not tested.
Recommended Dilution:Immunohistochemistry: FrozenOptimal dilutions to be determined by the researcher.
Positive Control:olon cell line HCT116
Storage and Stability:May be stored at 4℃ for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20℃.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ug
抗体種類：Mab
宿主：mouse
Source Antibody：human
Grade：Purified
Purity：Purified
Form：Supplied as a liquid in PBS, pH 7.6, 0.09% sodium azide.
Specificity：Recognizes human APC at ~300kD. Species Crossreactivity: mouse
Clone # USB：C-APC 28.9
Isotype：IgG1,k
Calc Applications Abbrev：IF IHC IP WB
Calc Crossreactivity：Hu Mo
Immunogen：Human APC C-terminal fusion with MBP (maltose binding protein).
