CD64 is a 72 kD single chain type I glycoprotein also known as FcγRI and FcR I.
CD64 is a member of the immunoglobulin superfamily and is expressed on monocytes/macrophages, dendritic cells, and activated granulocytes.
The expression can be upregulated by IFN-γ stimulation.
CD64 binds IgG immune complex.
It plays a role in antigen capture, phagocytosis of IgG/antigen complexes, and antibody-dependent cellular cytotoxicity (ADCC).
Applications:Suitable for Flow Cytometry.
Other applications not tested.
Recommended Dilution:Flow Cytometry: ≤2ug labels 10e6 cells in 100ul
Optimal dilutions to be deteremined by the researcher.
Storage and Stability:Store product at 4℃ if to be used immediately within two weeks.
For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20℃.
Aliquots are stable at -20℃ for 12 months after receipt.
Dilute required amount only prior to immediate use.
Further dilutions can be made in assay buffer.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ug
抗体種類：Mab
宿主：mouse
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by affinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide. Labeled with Biotin.
Specificity：Recognizes the EC3 epitope of human CD64 Species Crossreactivity: Cynomolgus monkey and Rhesus monkey. Preferentially binds to CD64A (FcγRIA), but not CD64B (FcγRIB).
Clone # USB：3H1631 (10.1)
Isotype：IgG1,k
Calc Applications Abbrev：FC
Calc Crossreactivity：Hu Mk
Immunogen：Human rheumatoid synovial fluid cells and fibronectin-purified monocytes.
