CD1c (also known as R7 or BDCA1) together with CD1a and b, belongs to group 1 of CD1 antigens.
These non-classical MHC-like glycoproteins serve as antigen-presenting molecules for a subset of T cells that responds to specific lipids and glycolipids found in the cell walls of bacterial pathogens or self-glycolipid antigens such as gangliosides, and they have also roles in antiviral immunity.
The trafficking routes of the particular CD1 types differ and correspond to their ability to bind and present different groups of antigens.
CD1c is unique in its ability to present e.g.
mycobacterial phosphoketides and polyisoprenoids.
CD1c is the only CD1 isoform that has been shown to interact both with alpha/beta and gamma/delta T cells.
Applications:Suitable for use in Flow Cytometry, Immunohistochemistry and Immunoprecipitation.
Other applications not tested.
Recommended Dilutions:Flow Cytometry: 1-4ug/mlOptimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4℃ for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20℃.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ug
抗体種類：Mab
宿主：mouse
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by Protein A affinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.4, 15mM sodium azide.
