CD117 is a 145kD immunoglobulin superfamily member also known as c-Kit and stem cell factor receptor (SCFR).
It is a transmembrane tyrosine-kinase receptor that binds the c-Kit ligand (also known as steel factor, stem cell factor, and mast cell growth factor).
CD117 is expressed on hematopoietic stem cells (including multipotent hematopoietic stem cells, progenitors committed to myeloid and/or erythroid lineages, and T and B cell precursors), mast cells, and acute myeloid leukemia (AML) cells.
CD117 interaction with its ligand is critical for the development of hematopoietic stem cells.
Applications:Suitable for use in Immunoprecipitation, Immunohistochemistry and Flow Cytometry.
Other applications not tested.
Recommended Dilution:Immunohistochemistry: acetone fixed frozen sectionsFlow Cytometry (Immunofluorescence staining): ≤0.06ug/10e6 cells in 100ulOptimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4℃ for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20℃.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：500ug
抗体種類：Mab
宿主：rat
Source Antibody：mouse
Grade：Affinity Purified
Purity：Purified by affinity chromatography.
Form：Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Specificity：Recognizes mouse CD117. Does not block c-Kit activity.
