CD49e is a type I integral membrane glycoprotein, known as α5 integrin, VLA-5 α chain.
It forms noncovalent heterodimer with integrin β1 (CD29).
CD49e contains two disulfide-linked subunits of 135 kD and 24 kD, and is mainly expressed on thymocytes, activated lymphocytes, endothelial cells, osteoblasts, melanoma, and some myeloid leukemia cells.
CD49e/CD29 complex binds to fibronection and neural adhesion molecule L1.
It mediates monocytes migration, involves in the regulation of cells survival and apoptosis, and co-stimulates T cell activation.
Applications:Suitable for use in Flow Cytometry.
Other applications not tested.
Recommended Dilutions:Flow Cytometry: 5ul labels 10e6 cells in 100ulOptimal dilutions to be determined by researcher.
Storage and Stability:Store product at 4℃ if to be used immediately within two weeks.
For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20℃.
Aliquots are stable at -20℃ for 12 months after receipt.
Dilute required amount only prior to immediate use.
Further dilutions can be made in assay buffer.
Caution: FITC conjugates are sensitive to light.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100Tests
抗体種類：Mab
宿主：mouse
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by affinity chromatography.
Form：Supplied as a liquid in PBS, 0.1% BSA, 0.09% sodium azide. Labeled with fluorescein isothiocyanate (FITC).
Specificity：Recognizes human CD49e. Species Crossreactivity: Cynomolgus, Rhesus
