DM1 （mertansine） is a thiol-containing derivative of maytansine.
It binds to tubulin and inhibits the assembly of microtubules.
DM1 is used to prepare ADCs （antibody-drug conjugates）, such as trastuzumab emtansine （abbreviated as T-DM1）.
This BSA-DM1 conjugate is designed with similar linker chemistry as T-DM1 and is synthesized at CellMosaic® for our customers' usage in immunization or immunoassay.
Maleimide functional groups are first introduced to the BSA followed by a reaction of the maleimide group with the thiol of DM1 to form the BSA-DM1 conjugate.The final conjugate is lyophilized from phosphate buffered saline containing sugar-based stabilizer for easy shipping and storage.
The product is sold as either 1 vial of 1 mg （Cat# CM52110-1MG） or 5 vials of 1 mg （Cat# CM52110-5MG）.
