Alprenolol is an antagonist for B1 and B2 adrenergic receptors.
Alprenolol agarose affinity chromatography was first introduced by Lefkowitz R. J. in 1979 for the purification of erythrocyte B-adrenergic receptor based on ligand-receptor interactions.
It is now routinely used for the purification of functionally active B1 and B2-adrenergic receptor.
CellMosaic's SepSphere™ Alprenolol Agarose is composed of Agarose 4B Beads linked to alprenolol via a thiol ether linkage.