概要：A204 cells are human epithelial cells derived from the muscles of a 1-year-old female patient with rhabdomyosarcoma.
With applications in 3D cell culture and tumorigenic properties, A-204 cells provide an opportunity for studying tumour biology and potential therapeutic interventions.
Derived from muscle tissue, A-204 cells closely resemble the outer layer of cells found in organs and tissues.
A-204 cells exhibit adherent growth, have an epithelial morphology and have a karyotype characterized by diploidy and tetraploidy.
Furthermore, these cells have demonstrated tumorigenicity, forming malignant tumours consistent with embryonal rhabdomyosarcoma in mice, validating their relevance in cancer research.
The presence of specific isoenzymes, including AK-1, ES-D, G6PD, GLO-I, Me-2, PGM1, and PGM3, in A-204 cells provides insight into their metabolic characteristics.
These isoenzymes may play a role in understanding cellular processes involved in cancer progression and treatment response.
With a doubling time of approximately 36 hours, A-204 cells exhibit rapid proliferation, allowing efficient experimentation and ensuring an ample supply of cells for research applications.
