概要：DSL-6A/C1 is a pancreatic ductal cell line derived from the DSL-6 transplantable acinar cell carcinoma.
The DSL-6 tumor was established in 1986 from a primary acinar cell carcinoma of the pancreas which developed in a male Lewis rat(DSL-101-79) that was given azaserine intraperitoneally.
The cultured DSL-6A/C1 tumor cells initially produced amylase, but production of exocrine enzymes ceased after 1 to 2 weeks in culture.
The cell line also lost structural and immunohistochemical acinar cell markers while acquiring duct cell markers during culture and regrafting.
The DSL-6A/C1 cell line expresses the ductal marker cystic fibrosis transmembrane regulator (CFTR).
仕様
容量：1vial
カテゴリー：Rat cell lines
Organism：Rat
Tissue：Pancreas
Disease：Carcinoma, azaserine induced
Metastatic Site：Ductal
Synonyms：DSL-6A/C1, DSL6A/C1
Breed：Lewis
Age：2 years
Gender：Male
Morphology：Epithelial-like
Cell Type：Acinar cells
Growth Properties：Adherent
Citation：DSL-6A-C1 (Cytion catalog number 500166)
Biosafety Level：1
Tumorigenic：Yes, in Lewis rats the cells produce solid tumors composed of ductlike structures surrounded by dense fibrous tissue
