概要:The 3T6-Swiss albino cell line, established by G.
Todaro and H.
Green in 1963 from disaggregated Swiss mouse embryos, is well-known in vitro model for cell growth and differentiation.
These cells are useful for studying extracellular matrix biology and tissue engineering because they secrete collagen and hyaluronic acid.
21% of 3T6-Swiss albino cells have an extra large chromosome with a terminal centromere and 21% have minute chromosomes, indicating an unstable karyotype in the stemline range (78-81), which makes them a great tool for studying chromosomal instability.
The 3T6-Swiss Albino cells have also been used to study oncogenes and tumor suppressor genes.
Other properties of the 3T6-Swiss Albino cell line are that they are non-tumorigenic and highly homogeneous.
The 3T6-Swiss Albino cell line is useful for studying basic cellular biology, extracellular matrix biology, chromosomal instability, and cancer therapeutics and tissue engineering.
仕様
容量:1vial
カテゴリー:Mouse cell lines
Organism:Mouse
Tissue:Embryonic
Applications:This cell line is an optimal choice for transfection.
Ploidy Status:Karyotyping results revealed an unstable range of 78-81. A significant portion (21%) of the cells contained a terminal centromere on a large chromosome, and another 21% comprised minuscule chromosomes.