概要:Introducing B16-F0 cells, a valuable resource for biological research in animal cells.
These cells, derived from Mus musculus (mouse), belong to the Eukaryota kingdom and the Animalia, Metazoa, Chordata, and Vertebrata phyla.
They are specifically obtained from the skin tissue of mice and classified as spindle-shaped and epithelial-like cells, presenting a mixture of both morphologies.
B16-F0 cells are significant in studying melanoma, a highly malignant skin cancer.
With an estimated 55,100 new invasive cases diagnosed annually in the USA, and a corresponding 7,910 fatalities, melanoma remains one of the deadliest cancers worldwide.
Current treatment options, such as surgical intervention, often fall short in advanced and metastatic cases, necessitating the development of improved therapeutic approaches.
In biological research, B16-F0 cells serve as a valuable model for studying metastasis and solid tumour formation, making them instrumental in advancing our understanding of these critical processes.
They have proven to be practical tools in investigating the biology of melanoma and have been extensively utilized in preclinical studies focused on developing new therapeutic strategies.
One particular application of B16-F0 cells is their use in 3D cell culture systems.
The ability to grow these cells in a three-dimensional environment mimics the in vivo conditions more closely, allowing researchers better to study the complex interactions and behaviour of melanoma cells.
This approach enhances the relevance and translatability of experimental findings, providing valuable insights into melanoma progression and potential therapeutic targets.
B16-F0 cells offer researchers a versatile and highly relevant model for investigating melanoma and its associated processes.
Their unique characteristics, derived from mouse skin tissue, make them an invaluable resource for understanding tumour biology, developing new therapeutic approaches, and combating melanomas devastating impact.
仕様
容量:1vial
カテゴリー:Mouse cell lines
Organism:Mouse
Tissue:Skin
Disease:Mouse melanoma
Synonyms:B16/F0, B16F0
Breed:C57BL/6
Gender:Male
Morphology:mixture of spindle-shaped and epithelial-like cells