概要:The TM4 cell line is reported to respond to FSH with an increase in cAMP production, but to not respond to luteinizing hormone(LH).
The FSH responsiveness is much reduced compared to primary sertoli cell cultures.
Constitutive plasminogen activator production is reported to be low, but is stimulated by FSH and, to a greater extent, by retinoic acid.Tested and found negative for ectromelia virus(mousepox).