特徴
- 概要：The murine cell line C127I, derived from malignant neoplasms of the mammary gland, exhibits a distinctive epithelial nature, rendering it a valuable asset for a variety of applications in research.
- Notably, C127I cells have undergone genetic modification through the introduction of a chimeric plasmid comprising bovine papillomavirus and the human interferon (HuIFN) gene, particularly IFN-gamma or IFN-alpha 5, regulated by the Simian virus 40 early promoters.
- This genetic transformation results in the maintenance of 30-50 extrachromosomal copies of the hybrid plasmid and the continuous secretion of elevated levels of HuIFNs.
- As a result, Mouse C127I Cells present an exciting opportunity for researchers to investigate the expression and functions of diverse proteins and their implications on biological systems, offering a valuable model system for studying mammary biology and related diseases.
- For example, C127I cells serve as a versatile platform for various applications, including acting as a transfection host for the transformation with bovine papillomavirus DNA plasmids, facilitating the visualization of sarcoma virus-induced foci, and enabling quantitative in vitro assays for bovine papilloma virus research, further enhancing their utility in scientific investigations.
仕様
- 容量：1vial
- カテゴリー：Mouse cell lines
- Organism：Mouse
- Tissue：Breast, mammary gland
- Disease：Carcinoma
- Applications：Transfection host for transformation with bovine papilloma virus DNA plasmids. Visualization of sarcoma virus-induced foci. Quantitative in vitro assays for bovine papilloma virus.
- Synonyms：C 1271, C-127I, C-127 I, CNC 127I
- Breed：RIII
- Gender：Female
- Morphology：Epithelial-like
- Growth Properties：Adherent
- Citation：C127I (Cytion catalog number 400134)
- Biosafety Level：1
- Viruses：Negative for ectromelia virus (mousepox).
- Virus Susceptibility：Bovine papilloma virus
- Reverse Transcriptase：Negative (as determined in supernatant fluid)
- 非営利団体（アカデミア）様向けの価格です。営利企業様や営利目的での販売は実施しておりません。
- 購入にはメーカーの「Non Profit Supply Agreement」及び弊社の「ヒト生体試料の提供に関する同意書」への記入が必要となる場合がございます。
- この商品は法規制を確認しておりません｡(法規制によって販売できない場合もございます)
- 【試薬に関するお問合せ】
- アズワン株式会社 試薬・プロセス材料グループ
- TEL：06-6447-8641
- FAX：06-6447-8642
- E-mail：[email protected]
よくあるご質問（FAQ）
掲載カタログ情報
| 掲載カタログ名 | 掲載ページ |
|---|