Tumorigenic:Yes, in immunotolerant rats and nu-nu mice
Karyotype:The stemline chromosome number is hypotetraploid, with the 2S component occurring at 4.4%. Marker chromosomes 1p, t(1q,11q), 11q+, t(13,?), 16q+, t(12q, 18q). M10, t(2q,13q), i(15), and ?t(xp,21q) occurred in all S metaphases, and t(1p,?), t(1p,14q), t(16,?), and t(14,21) occurred in some. In addition, 4 to 9 small markers of unidentifiable origin occurred frequently. Chromosome No. 7 was generally hexasomic, x chromosomes were disomic, and normal No. 15 was absent. No Y chromosome was detected in the QM stained preparation. Phenotype Frequency Product: 0.00003