Tumorigenic:Yes, in nude mice. Forms poorly differentiated carcinoma
Mutational Profile:CaLu-6 cells carry a mutation in KRAS codon 61, c.181C|BiggerAs|A p.(Gln61Lys). NRAS of BRAF mutation was not detected.
Karyotype:The stemline chromosome number is hypotriploid and the 2S component occurred at 5.8%. Modal chromosome number is 59. Fourteen marker chromosomes (constitutive) were common to most S metaphases. No Y chromosome was detected in the QM stained preparation.